Jul 7 2018

AdvantaPass Cleanroom Pass Through Technology – Clean Room Wall and Bulkhead Pass Thru Port, pharmaceutical

AdvantaPass – Clean Room Pass Through Technology

Pharmaceutical clean roomAdvantaPass is a patented system that permits the aseptic transfer of fluids between the walls of pharmaceutical manufacturing suites. It’s the first system of its kind to offer complete isolation between different classes of clean rooms when transferring multiple lines of fluid through a single stainless steel pass-through wall portal.

AdvantaPass provides a practical, safe, secure and easy way to move large volumes of liquids from one room to another without the risk of bin breakage or spillage. Its incorporation of Single-Use disposable components eliminates cleaning validation requirements that involve the expense and waste of time, labor and natural resources.


  • Pharmaceutical clean roomSingle-Use components eliminate the need to clean and validate traditional hard piping transfer lines
  • Design flexibility — can be used in new construction or retrofitted into existing facilities; no welding involved
  • Accommodates single or multiple fluid flow lines without compromising the isolation barrier functionality
  • Provides a reliable method for transferring fluids without physically moving bins and totes, thereby eliminating the risk of breakage, spillage and lost pharmaceutical product during bin transfer
  • Uses Single-Use process components made of either platinum-cured silicone or TPE tubing and isolator flanges and seals
  • Custom manufactured with standardized parts for each application including a choice of end connections
  • Does not involve multiple moving parts or frequent maintenance like other in-wall pass thru systems
  • Works with various wall and floor thicknesses
  • Assembly and disassembly takes just minutes
  • Standard sizes up to 6 diameter; larger sizes on request
  • Portal assemblies machined from solid 316L stainless steel
  • Purge ports further reduce the chance of cross contamination between non-viral-active and viral-active suites
  • U.S. Patent 8,870,230


The AdvantaPass cleanroom pass thru system is custom produced to accommodate different wall thicknesses. It can also be adapted for floor-to-ceiling conveyance.

AdvantaPass uniquely manages multiple tubing apertures, as well as purge ports, through a single wall portal. The pass-through system can save thousands of dollars as compared to other pass-through methods that involve numerous moving parts and frequent maintenance.

AdvantaPass reduces production stoppages for sterilization and validation of hard piping transfer systems, which use natural resources, cleaning chemicals that must be disposed of, time and labor. The system’s Single-Use components allow for flexibility from one transfer to the next, minimize the risk of cross contamination and increase productivity and efficiency.

Pharmaceutical clean room



Pharmaceutical clean roomAdvantaPass uses 316L stainless steel components such as portal assemblies, end caps and hygienic union clamps to form a secure barrier, while it incorporates single use tubing, seals, gaskets and isolator assemblies for fluid transfer processes. AdvantaPass is offered in standard sizes up to 6 diameter with larger dimensions available on request.

Note: The use of non-BPE-compliant components may result in an improper isolator seal.


Single or multiple tubing ports, where one pass-thru system can serve several different tubes, is unique to AdvantaPass.

Choose from aseptic or open connector configurations to adapt to your process. Single or double isolation barriers maintain the proper environment.

Purge ports are available to filter any potential transfer of viral- active product from one suite to another. Purge ports also introduce filtered air, creating a pressurized portal for complete isolation between classified areas.

Pharmaceutical clean roomDownload a printable version of our AdvantaPass brochure. AdvantaPass_Pass-Through_Technology.pdf (627kb)

Pharmaceutical clean room

Pharmaceutical clean room

Pharmaceutical clean room

Pharmaceutical clean room

This cross section view of the AdvantaPass system shows an air purge filtering function.

Pharmaceutical clean room


Pharmaceutical clean room


AdvantaPure specializes in the design and manufacture of molded Single-Use manifold assemblies for sampling and storage applications. These assemblies are available in platinum-cured silicone or biopharm grade TPE .

Pharmaceutical clean room



Low-volatile grade, platinum-cured silicone tubing is clean-room produced for critical pharmaceutical, biomedical, cosmetic, and food applications. APST has undergone extensive physical, chemical, and biological testing and meets USP Class VI, FDA, ISO, European Pharmacopoeia, and 3-A standards.

Pharmaceutical clean roomPharmaceutical clean room

Pharmaceutical clean room



AdvantaFlex addresses the need for a sterilizable, moldable, heat sealable and weldable biopharmaceutical tubing that does not contain silicone oils. AdvantaFlex maintains its physical properties following sterilization processes, resists kinking, remains translucent for visible product flow, and does not become gummy. Its unique properties help it outperform similar tubing in peristaltic pumps.

Pharmaceutical clean room

Pharmaceutical clean roomВ В В В Pharmaceutical clean roomВ В В В Pharmaceutical clean roomВ В В В Pharmaceutical clean roomВ В В В Pharmaceutical clean room

AdvantaPure products are produced by NewAge Industries, Inc., 145 James Way, Southampton, PA 18966 USA

Phone: 215-526-2151 888-755-4370 (toll free US only); Fax: 215-526-2167 888-258-4293 (toll free US only); Email: [email protected]

2001-2017 NewAge Industries, Inc. All rights reserved worldwide.

Written by admin

Leave a Reply

Your email address will not be published. Required fields are marked *